Haematology

APTT

Blue Topped citrate Vacuette

3.5ml

See Turnaround Times

Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours.

Adult range

BLEEDING TIME

Please contact the Consultant Haematologist to arrange. The patient must not have taken aspirin for one week beforehand

Interpretation will be quoted with the result.

CHROMOSOME STUDIES

Green topped lithium heparin

6ml

2 weeks

Samples are referred to St Georges. Special arrangement with laboratory is necessary.

n/a

CLOTTING SCREEN

Blue Topped citrate Vacuette

3.5ml

See Turnaround Times

Screen comprises PT and APTT. See APTT

Refer to APTT, PT,INR

FIBRINOGEN

Blue Topped citrate Vacuette

3.5ml

See Turnaround Times

Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours.

1.8-4.0g/L

FACTOR ASSAYS
II,V,VII,VIIIc,FIX,X,XI,XII

Blue Topped citrate Vacuette

2x3.5ml

2-3 Weeks

Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours.

50-150 u/dL

AT III

Blue Topped citrate Vacuette

3.5ml

2-3 Weeks

Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours.

82/128 u/dL

Protein C

Blue Topped citrate Vacuette

3.5ml

2-3 Weeks

Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours.

70-140 u/dL

Protein S(free Ag)

Blue Topped citrate Vacuette

3.5ml

2-3 Weeks

Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours.

54.7-123.7 u/dL

APCR (Modified)

Blue Topped citrate Vacuette

3.5ml

2-3 Weeks

Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours.

2.61-3.32 ratio

LUPUS TESTS

Blue Topped citrate Vacuette

2 x 3.5ml

2-3 weeks

Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours.

D-DIMER

Blue Topped citrate Vacuette

3.5ml

See Turnaround Times

A specific fibrin degradation product. Levels found in DIC, DVT/PE, thrombolytic therapy.

<230 ng/ml as a negative predictor in DVT/PE.

DIRECT COOMBS TEST

Purple topped EDTA

2ml

See Turnaround Times

Suggest discuss with Consultant Haematologist.

Reported as POS/NEG

ESR

Mauve topped long tube (citrate) monovette

3.5ml

See Turnaround Times

Should be processed on the day of venesection
*vacuum the tube before use*

Adult range
Note: age and sex dependent, refer to individual report for range.

FULL BLOOD COUNT

Purple topped EDTA

2ml

See Turnaround Times

Age dependent, parameters refer to individual report for range.

G-6-P-DEHYDROGENASE

Purple topped EDTA

2ml

3 days

Quantitation studies performed at reference centre.

Screening test reported as normal or deficient.

Hb A2

Purple topped EDTA

2ml

3 days

Hb electrophoresis

Purple topped EDTA

2ml

1 week
ANC samples within 3 working days

Full interpretive comments on the report.

INR

Blue topped citrate

3.5ml

See Turnaround Times

A derived value from the prothrombin time for patients taking warfarin. Coagulation samples must be processed on the day the sample is taken.

Therapeutic ranges for patients on oral anticoagulants.

MALARIA PARASITES

Purple topped EDTA

2ml

See Turnaround Times
Sample should be sent to lab immediately

Repeated examinations of blood film may be necessary if parasites not identified and there is clinical suspicion of infection. Positive results are confirmed with Malaria Reference Laboratory. Please indicate pertinent travel history and anti-malarial prophylaxis.

Reported as POS/NEG.
A positive result will have further information.

MONOSPOT

Purple topped EDTA
Can be tested from the FBC sample.

2ml

See Turnaround Times

Test may remain positive for many months after initial episode of infectious mononuclieosis. Further confirmatory tests of infection should be discussed with Consultant Haematologist or Consultant Microbiologist.

Reported as POS/NEG

PROTHROMBIN TIME (PT)

Purple topped EDTA

3.5ml

See Turnaround Times

Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours.

Adult reference range9.5 - 12.0 secs.

PYRUVATE KINASE

Purple topped EDTA

2ml

3 days

Screening test for the deficiency, which is autosomally inherited. Quantitation studies performed at reference centre.

Screening test reported as normal or deficient.

RETICULOCYTES

Purple topped EDTA

2ml

See Turnaround Times

Reticulocytes reflect the rate of red cell production. In states of bleeding, haemolysis, and recovery from marrow suppression. The EDTA sample must be processed on the day of venesection

Adult range
20 – 100 x 109/l

Note: age dependent, refer to individual report for range